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Cheap Flights from Santo Domingo (SDQA) to Medellin (MDEA)

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Find the cheapest month or even day of the year to fly to Medellin

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Flight deals from Santo Domingo to Medellin

Looking for a cheap last-minute deal or the best return flight from Santo Domingo to Medellin? Find the lowest prices on one-way and return tickets right here.
Medellin.£151 per passenger.Departing Thu, 7 May, returning Tue, 12 May.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Thu, 7 May, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Tue, 12 May, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From £151, select.
Medellin.£152 per passenger.Departing Tue, 3 Mar, returning Thu, 5 Mar.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Tue, 3 Mar, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Thu, 5 Mar, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From £152, select.
Medellin.£159 per passenger.Departing Wed, 28 Jan, returning Wed, 11 Feb.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Wed, 28 Jan, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Wed, 11 Feb, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From £159, select.
Medellin.£161 per passenger.Departing Fri, 20 Feb, returning Tue, 24 Feb.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Fri, 20 Feb, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Tue, 24 Feb, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From £161, select.
Medellin.£162 per passenger.Departing Tue, 13 Jan, returning Sat, 24 Jan.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Tue, 13 Jan, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Sat, 24 Jan, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From £162, select.
Medellin.£162 per passenger.Departing Sat, 18 Apr, returning Fri, 24 Apr.Return flight with Arajet.Outbound direct flight with Arajet departs from Santo Domingo Las Americas on Sat, 18 Apr, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Arajet departs from Medellin Jose Maria Cordova on Fri, 24 Apr, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From £162, select.
Medellin.£163 per passenger.Departing Thu, 2 Jul, returning Tue, 7 Jul.Return flight with Wingo.Outbound direct flight with Wingo departs from Santo Domingo Las Americas on Thu, 2 Jul, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Wingo departs from Medellin Jose Maria Cordova on Tue, 7 Jul, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From £163, select.
Medellin.£163 per passenger.Departing Thu, 30 Apr, returning Tue, 5 May.Return flight with Wingo.Outbound direct flight with Wingo departs from Santo Domingo Las Americas on Thu, 30 Apr, arriving in Medellin Jose Maria Cordova.Inbound direct flight with Wingo departs from Medellin Jose Maria Cordova on Tue, 5 May, arriving in Santo Domingo Las Americas.Price includes taxes and charges.From £163, select.

Find the cheapest month to fly from Santo Domingo to Medellin

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santo Domingo to Medellin flights are currently cheapest in May.
Dec
from £257
Jan
from £162
Feb
from £161
Mar
from £152
Apr
from £162
May
from £151
Jun
from £176
Jul
from £163
Aug
from £238
Sep
from £202
Oct
Find prices
Nov
from £278

Direct flights from Santo Domingo to Medellin

Alternative Santo Domingo to Medellin routes

Looking for the cheapest, fastest or easiest route from Santo Domingo to Medellin? You could fly into the following airports instead.

Santo Domingo to Medellin: Flight information

The things to know before you go.
Cheapest flight found£151
Cheapest month to flyMay
Average flight time2 hrs, 32 mins
Most popular airlineArajet
Average flights per week29

Finding cheap flights from Santo Domingo to Medellin: Frequently asked questions

There are 2 airports in Medellin: Medellin Enrique Olaya Herrera and Medellin Jose Maria Cordova.
The best price we found for a return flight from Santo Domingo to Medellin is £151. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 32 minutes is the average flight time from Santo Domingo to Medellin.
Arajet, World Ticket Ltd and Copa Airlines Colombia fly direct from Santo Domingo to Medellin.
As of December 2025, there are 29 flights per week flying from Santo Domingo to Medellin.
The cheapest month to fly from Santo Domingo to Medellin is usually May.
If you're flying from Santo Domingo, the cheapest airport near Medellin is Medellin Jose Maria Cordova – which is 11.8 miles away from the centre of Medellin. We've found flights into this airport from £151.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Santo Domingo to Medellin on Thursday, 7 May 2026.
Yes – the average flight time is 2 hours and 32 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Medellin but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Medellin is around 40 days in advance, so don’t leave your flight to the last minute.
In December, the average temperature is usually around 18°C. May is typically the warmest month in Medellin, when it usually averages around 21°C. You can expect the least rain in January. The coldest month is November, with temperatures averaging 15°C. The rainiest month is May.
The cheapest airline that flies to Medellin is Arajet .

Travelling from Santo Domingo to Medellin: what you need to know

  • Start your holiday planning by considering where you'll catch your flight from Santo Domingo to Medellin. Las Americas International Airport (SDQ) and Dr. Joaquin Balaguer International Airport (JBQ) are Santo Domingo's main airports.

  • Jose Maria Cordova International Airport (MDE) is where you'll be arriving in Medellin.

  • The average time for a direct Santo Domingo to Medellin flight is 2 hours 35 minutes.

  • The timezone in Medellin is UTC-5, which is one hour behind Santo Domingo.

  • The most popular route for flights from Santo Domingo to Medellin is from Las Americas International Airport (SDQ) to Jose Maria Cordova International Airport (MDE). You can choose from nine weekly services between these two airports. If you want to be on your way as soon as possible, the earliest flight from SDQ to MDE is the 06:00 Arajet service. If you have other commitments or plans on your day of travel, the final departure is at 19:10 with Arajet.

  • To ensure you make your Santo Domingo to Medellin flight, leave enough time for things like baggage drop and finding your gate. Turning up two hours ahead of international departures and an hour before domestic flights is the general travel rule.

  • During popular months like August, it's best to get to the airport well in advance. Plan to arrive two hours before domestic departures and four hours ahead for international flights whenever you're travelling during high season in general.

How to find the cheapest flights from Santo Domingo to Medellin

  • Score cheap Santo Domingo to Medellin flights by booking two months ahead. Based on our research, that's the ideal time for finding the biggest deals.

  • The best month for landing cheap plane tickets from Santo Domingo to Medellin is May. Use the 'Whole month' tool to compare prices, then choose the dates that offer the biggest savings.

  • Spend less time searching for cheap flights from Santo Domingo to Medellin by setting up a Price Alert. You'll receive an email or notification through the app when a lower fare pops up.

  • Choose your preferred departure and arrival times, number of stops and airlines by using the filters. Or sort your Santo Domingo to Medellin flight results by 'Fastest,' 'Best' or 'Cheapest.'

Flying from Santo Domingo

Las Americas International Airport (SDQ)

  • You can book a direct flight from Santo Domingo to Medellin jetting off from Las Americas International Airport (SDQ). Begin your journey at SDQ and arrive at Jose Maria Cordova International Airport (MDE).

  • Arajet is a popular airline that offers direct Santo Domingo to Medellin plane tickets leaving from SDQ.

  • We make it a cinch to find a Santo Domingo to Medellin flight with a stopover. To see the options leaving from Las Americas International Airport, deselect 'Direct flights only.' Next, select a flight that has a stop long enough to see the sights of the city of your choice. Major stopovers include:

    • El Dorado International Airport (BOG)

    • Rafael Nunez International Airport (CTG)

    • Simon Bolivar International Airport (CCS)

  • To reach SDQ from central Santo Domingo, it takes around 30 minutes if you're going by car. It's roughly 27 kms (17 miles) from the airport to the city centre.

  • Want a stress-free start to your travels? Stay near Las Americas International Airport. Whether you have an early flight from Santo Domingo to Medellin or just don't want to be rushed, these hotels have you covered:

  • 72.45% of flights departing from Las Americas International Airport land at their destination on schedule.

Arriving in Medellin

Jose Maria Cordova International Airport (MDE)

  • The distance from Jose Maria Cordova International Airport (MDE) to central Medellin is roughly 18 kms (11 miles). It'll take you about 35 minutes to reach the centre driving.

  • The last thing you want is a lengthy journey to your hotel if you're arriving on a late flight from Santo Domingo to Medellin. Check in to one of these accommodation options near MDE instead:

  • Get your adventure underway by picking up a Jose Maria Cordova International Airport rental car. Grab your wheels from Localiza, Green Motion or Confort Rent a Car to explore Medellin and beyond.

  • Lock in the best rate by booking your vehicle from Jose Maria Cordova International Airport around one week in advance of your trip.

Enrique Olaya Herrera Airport (EOH)

  • Enrique Olaya Herrera Airport (EOH) is roughly 3 kms (2 miles) from central Medellin. Once you've hopped off your flight from Santo Domingo to Medellin, it takes approximately 15 minutes to reach the heart of the city in a cab or ride-share.

  • If you choose to travel on public transport, you'll reach the centre in 30 minutes or so.

  • Why wait around for a cab? An Enrique Olaya Herrera Airport rental car lets you get going right away. Turn up the music and hit the open road with a set of wheels from Confort Rent a Car or Green Motion.

  • Avoid potential price surges. Securing your ride one week ahead of your arrival at EOH can get you a lower rate.

Best time to go to Medellin

  • It's time to work out your trip dates for your flight from Santo Domingo to Medellin. August is the most popular month to visit Medellin. If you want a quieter atmosphere, go in April.

  • The warmest month in Medellin is August, with temperatures ranging between 11ºC (52ºF) and 27ºC (81ºF). Lock in your Santo Domingo to Medellin ticket then if that's your definition of good weather.

  • If you like travelling in cooler conditions, look for a cheap flight from Santo Domingo to Medellin in July when temperatures average between 11ºC (52ºF) and 27ºC (81ºF).

More about Medellin

  • When it comes to looking for somewhere to lay your head, you'll find the best places to stay in Medellin right here. Check out these hotels once you've booked your flight from Santo Domingo to Medellin:

  • Parque Arvi and Botero Plaza are just the start of the popular attractions to add to your Medellin must-do list. Keep the momentum going by heading to Pueblito Paisa.

Explore more of Colombia

  • Medellin will leave a lasting impression, but there are so many other corners of Colombia you'll want to see. Around 150 miles south-east of Medellin, a trip to Bogota will keep you on the go. Start with attractions like Gold Museum, Usaquen Train Station and Urbanización Villas del Madrigal - Molino del Viento Park.

  • If you're looking to explore another major stop in Colombia, head for Cali, roughly 200 miles south of Medellin. Cristo Rey, Gato de Tejada and Caliwood Museo de la Cinematografia are the start of reasons to visit.

More travel options

Plan the rest of your trip from Santo Domingo to Medellin

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.