Cheap Flights from Madrid (MAD) to Santiago (STI)

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Travellers and cabin class, 1 Adult, Economy

Compare Madrid to Santiago flight deals

Find the cheapest month or even day of the year to fly to Santiago

Book the best Santiago fare with no extra fees

Flight deals Cheapest month Find the best route Route info FAQs Tips and advice

Flight deals from Madrid to Santiago

Looking for a cheap last-minute deal or the best return flight from Madrid Airport to Santiago Airport? If you want to travel next month, return fares start from £615. Find the lowest prices on one-way and return tickets right here.

Santiago.£376 per passenger.Departing Wed, 19 Aug.One-way flight with Air Europa.Outbound direct flight with Air Europa departs from Madrid on Wed, 19 Aug, arriving in Santiago.Price includes taxes and charges.From £376, select.

Santiago.£377 per passenger.Departing Wed, 2 Sep.One-way flight with Air Europa.Outbound direct flight with Air Europa departs from Madrid on Wed, 2 Sep, arriving in Santiago.Price includes taxes and charges.From £377, select.

Santiago.£377 per passenger.Departing Sat, 13 Feb.One-way flight with Air Europa.Outbound direct flight with Air Europa departs from Madrid on Sat, 13 Feb, arriving in Santiago.Price includes taxes and charges.From £377, select.

Santiago.£377 per passenger.Departing Fri, 22 Jan.One-way flight with Air Europa.Outbound direct flight with Air Europa departs from Madrid on Fri, 22 Jan, arriving in Santiago.Price includes taxes and charges.From £377, select.

Santiago.£377 per passenger.Departing Wed, 25 Nov.One-way flight with Air Europa.Outbound direct flight with Air Europa departs from Madrid on Wed, 25 Nov, arriving in Santiago.Price includes taxes and charges.From £377, select.

Santiago.£388 per passenger.Departing Fri, 2 Oct.One-way flight with Air Europa.Outbound direct flight with Air Europa departs from Madrid on Fri, 2 Oct, arriving in Santiago.Price includes taxes and charges.From £388, select.

Santiago.£388 per passenger.Departing Wed, 3 Mar.One-way flight with Air Europa.Outbound direct flight with Air Europa departs from Madrid on Wed, 3 Mar, arriving in Santiago.Price includes taxes and charges.From £388, select.

Santiago.£426 per passenger.Departing Fri, 4 Dec.One-way flight with TAP Air Portugal.Outbound indirect flight with TAP Air Portugal, departs from Madrid on Fri, 4 Dec, arriving in Santiago.Price includes taxes and charges.From £426, select.

Santiago.£478 per passenger.Departing Sat, 22 May.One-way flight with Avianca.Outbound indirect flight with Avianca, departs from Madrid on Sat, 22 May, arriving in Santiago.Price includes taxes and charges.From £478, select.

Santiago.£480 per passenger.Departing Sat, 22 May.One-way flight with Air Europa.Outbound direct flight with Air Europa departs from Madrid on Sat, 22 May, arriving in Santiago.Price includes taxes and charges.From £480, select.

Santiago.£520 per passenger.Departing Fri, 4 Dec.One-way flight with Air Europa.Outbound direct flight with Air Europa departs from Madrid on Fri, 4 Dec, arriving in Santiago.Price includes taxes and charges.From £520, select.

Find the cheapest month to fly from Madrid to Santiago

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Madrid to Santiago flights are currently cheapest in August.

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Direct flights from Madrid to Santiago

Madrid to Santiago: Alternative routes

Compare routes from Madrid to Santiago below. You may find an airport to fly into that's cheaper, faster, or easier than Santiago.

Santiago

1 mile from central Santiago

ClosestCheapest

from £376

Search flights

Puerto Plata

23 miles from central Santiago

from £422

Search flights

Madrid to Santiago: Flight information

The things to know before you go.

Cheapest flight found	£376
Cheapest month to fly	August
Average flight time	8 hrs, 43 mins
Most popular airline	Air Europa
Average flights per week	4

Finding cheap flights from Madrid to Santiago: Frequently asked questions

How much are return flights from Madrid to Santiago?

The best price we found for a return flight from Madrid to Santiago is £601. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

How long does it take to fly from Madrid to Santiago?

8 hours and 43 minutes is the average flight time from Madrid to Santiago.

Which airlines fly direct from Madrid to Santiago?

Air Europa flies direct from Madrid to Santiago.

How many flights are there a week from Madrid to Santiago?

As of August 2026, there are 4 flights per week flying from Madrid to Santiago.

When is the cheapest time to fly from Madrid to Santiago?

The cheapest month to fly from Madrid to Santiago is usually October.

Which upcoming date is cheapest to fly from Madrid Airport to Santiago Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Madrid Airport to Santiago Airport on Thursday, 1 October 2026.

Can I get a direct flight from Madrid Airport to Santiago Airport?

Yes – the average flight time is 8 hours and 43 minutes.

How can I find the best flight deal to Santiago?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santiago but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Santiago?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santiago is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from Madrid Airport to Santiago with?

Currently, jetBlue and Air Europa offer the cheapest flight tickets to Santiago.

Flying from Madrid Airport (MAD) to Santiago Airport (STI): what you need to know

The average length of a direct flight from Madrid Airport to Santiago Airport is 8 hours 40 minutes.
Santiago is five hours behind Madrid and observes the UTC-4 timezone.
Arriving two hours before an international flight and one hour ahead of a domestic departure are travel rules worth sticking to. Be at the airport on time to board your MAD to STI flight.
Flying during a peak time such as July? School holidays and other high seasons can mean longer lines at airport checkpoints. Be extra cautious and arrive up to four hours ahead of international flights and two hours before a domestic departure.
Air Europa offers direct flights from Madrid Airport to Santiago Airport. Book with this popular carrier, then get ready to discover the sights in Santiago — and maybe even more of the Dominican Republic if your schedule allows.
The airline most travellers prefer to fly with on this route is Air Europa.
Among carriers operating MAD to STI flights, Air Europa has the highest rate of on-time arrivals.
We make it easy to book a flight with a stopover. To see all your options for tickets from Madrid Airport to Santiago Airport, deselect 'Direct flights only.' Then, pick a flight that has a stop long enough to explore the city of your choice. Worthwhile stopovers between MAD and STI include:
- New York John F. Kennedy Airport
- Miami International Airport
- Santo Domingo Las Americas Airport

How to find the cheapest flights from Madrid Airport (MAD) to Santiago Airport (STI)

The lowest price we've seen for a one-way Madrid Airport to Santiago Airport flight is £376. A round-trip ticket right now is £601. Depending on the availability and when you book, these fares could change.
To get cheap tickets from MAD to STI, reserve your journey 11 months ahead of your departure.
The cheapest month for flights from Madrid Airport to Santiago Airport is April. Use the 'Whole month' tool to find the lowest airfares if you have a flexible schedule.
Save time looking for cheap flights from MAD to STI by creating a Price Alert. You'll receive an email or notification on the app when fares go down.
Tailor your flights using filters. Choose your departure and arrival times, total journey duration and airlines. You can also sort your results by 'Cheapest,' 'Fastest' or 'Best' flights from Madrid Airport to Santiago Airport.

Handy information about Madrid Airport (MAD)

Of all flights leaving Madrid Airport, 77% arrive as scheduled at their destination.
To get to Madrid Airport from central Madrid, it takes around 20 minutes if you're travelling by car. Of course, this depends on traffic. It's approximately 13 kms (8 miles) from the airport to the city centre.
Catching public transport? You can expect a journey time of around 30 minutes.
Get your travels off to a relaxed start by staying near MAD. Whether you're boarding an early flight from Madrid Airport to Santiago Airport or want to avoid feeling rushed, these stays have you covered:

Arriving at Santiago Airport (STI)

Book a hotel close to STI if you're taking a late Madrid Airport to Santiago Airport flight. Settle into one of these accommodation options and avoid the hassle of a long transfer:
Pick up a Santiago Airport rental car and explore Santiago and beyond with your own set of wheels. America, Zezgo Rent a Car and Alamo are top providers you can book with here.
Booking your ride from Santiago Airport about one week ahead boosts your odds of scoring a great price.

Getting from Santiago Airport (STI) to central Santiago

Santiago Airport to the centre of Santiago has a drive time of about 25 minutes. It's approximately 16 kms (10 miles) away.
If you're travelling by public transport, expect a journey time of around 40 minutes.

When to fly to Santiago Airport (STI)

The quietest month for a flight from Madrid Airport to Santiago Airport is October, while August is the busiest. Choose the ideal time to go to Santiago based on whether you prefer a laid-back vibe or a more bustling atmosphere.
Book your flight from Madrid Airport to Santiago Airport for August if you'd like to go to Santiago during its warmest month. Expect temperatures of between 21ºC and 33ºC.
If you want to travel in cooler conditions, search for a cheap ticket from MAD to STI in January. Average temperatures are between 16ºC and 29ºC then.

Explore more of the Dominican Republic

Santo Domingo is just one of the many cities in the Dominican Republic waiting to be discovered after you've experienced Santiago. Around 137 kms (85 miles) away to the south-east, check out popular attractions including Catedral Primada de las Americas, Alcazar de Colon and The Cathedral of the Americas.
If there's time to check out another major stop in the Dominican Republic, head for Santo Domingo Este, about 145 kms (90 miles) south-east of Santiago. Lago los tres ojos, National Aquarium and La Cueva del Eden are highlights.