Cheap Flights from Manchester (MAN) to Knoxville (TYS)

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Compare Manchester to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

Book the best Knoxville fare with no extra fees

Flight deals Cheapest month Find the best route Route info FAQs Tips and advice

Flight deals from Manchester to Knoxville

Looking for a cheap last-minute deal or the best return flight from Manchester Airport to Knoxville Airport? If you want to travel next month, return fares start from £634. Find the lowest prices on one-way and return tickets right here.

Knoxville.£319 per passenger.Departing Mon, 2 Nov.One-way flight with Ryanair.Outbound indirect flight with Ryanair, departs from Manchester on Mon, 2 Nov, arriving in Knoxville.Price includes taxes and charges.From £319, select.

Knoxville.£345 per passenger.Departing Tue, 1 Dec.One-way flight with easyJet.Outbound indirect flight with easyJet, departs from Manchester on Tue, 1 Dec, arriving in Knoxville.Price includes taxes and charges.From £345, select.

Knoxville.£366 per passenger.Departing Sat, 9 Jan.One-way flight with Ryanair.Outbound indirect flight with Ryanair, departs from Manchester on Sat, 9 Jan, arriving in Knoxville.Price includes taxes and charges.From £366, select.

Knoxville.£369 per passenger.Departing Mon, 26 Oct.One-way flight with Ryanair.Outbound indirect flight with Ryanair, departs from Manchester on Mon, 26 Oct, arriving in Knoxville.Price includes taxes and charges.From £369, select.

Knoxville.£400 per passenger.Departing Sat, 27 Feb.One-way flight with easyJet.Outbound indirect flight with easyJet, departs from Manchester on Sat, 27 Feb, arriving in Knoxville.Price includes taxes and charges.From £400, select.

Knoxville.£431 per passenger.Departing Thu, 17 Sep.One-way flight with Jet2.Outbound indirect flight with Jet2, departs from Manchester on Thu, 17 Sep, arriving in Knoxville.Price includes taxes and charges.From £431, select.

Knoxville.£451 per passenger.Departing Tue, 23 Mar.One-way flight with Ryanair.Outbound indirect flight with Ryanair, departs from Manchester on Tue, 23 Mar, arriving in Knoxville.Price includes taxes and charges.From £451, select.

Knoxville.£551 per passenger.Departing Mon, 31 May.One-way flight with Virgin Atlantic.Outbound indirect flight with Virgin Atlantic, departs from Manchester on Mon, 31 May, arriving in Knoxville.Price includes taxes and charges.From £551, select.

Knoxville.£593 per passenger.Departing Thu, 1 Jul.One-way flight with Virgin Atlantic.Outbound indirect flight with Virgin Atlantic, departs from Manchester on Thu, 1 Jul, arriving in Knoxville.Price includes taxes and charges.From £593, select.

Knoxville.£614 per passenger.Departing Thu, 8 Apr.One-way flight with Delta.Outbound indirect flight with Delta, departs from Manchester on Thu, 8 Apr, arriving in Knoxville.Price includes taxes and charges.From £614, select.

Find the cheapest month to fly from Manchester to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Manchester to Knoxville flights are currently cheapest in November.

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Manchester to Knoxville: Alternative routes

Compare routes from Manchester to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Knoxville

11 miles from central Knoxville

ClosestCheapest

from £319

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Manchester to Knoxville: Flight information

The things to know before you go.

Cheapest flight found	£319
Cheapest month to fly	November

Finding cheap flights from Manchester to Knoxville: Frequently asked questions

How much are return flights from Manchester to Knoxville?

The best price we found for a return flight from Manchester to Knoxville is £571. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Manchester to Knoxville?

Currently, there are no airlines that fly direct from Manchester to Knoxville. But we found flights with one or more stops from £570.

How many flights are there a week from Manchester to Knoxville?

As of September 2026, there are no flights flying from Manchester to Knoxville.

When is the cheapest time to fly from Manchester to Knoxville?

The cheapest month to fly from Manchester to Knoxville is usually January.

Which upcoming date is cheapest to fly from Manchester Airport to Knoxville Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Manchester Airport to Knoxville Airport on Sunday, 10 January 2027.

Can I get a direct flight from Manchester Airport to Knoxville Airport?

No airlines currently offer direct flights between Manchester Airport and Knoxville Airport. Most routes have one or more stops.

How can I find the best flight deal to Knoxville?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Knoxville?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from Manchester Airport to Knoxville with?

Currently, Scandinavian Airlines offers the cheapest flight tickets to Knoxville.

Travelling from Manchester Airport (MAN) to McGhee Tyson Airport (TYS): what you need to know

Arriving two hours before an international flight and one hour ahead of a domestic departure are tried-and-true travel tips. Show up at the airport on time to board your MAN to TYS flight.
You'll likely experience longer queues during popular months such as August. Arriving up to four hours in advance for international flights and two hours for a domestic departure is a smart move.
We make it easy to book a flight with a stopover. To see all your options for tickets from Manchester Airport to McGhee Tyson Airport, uncheck 'Direct flights only.' Then, pick a flight with a stop long enough to explore the city of your choice. Popular stopovers between MAN and TYS include:
- Hartsfield-Jackson Atlanta International Airport
- Orlando International Airport
- George Bush Intercontinental Airport

How to find the cheapest flights from Manchester Airport (MAN) to McGhee Tyson Airport (TYS)

£319 is the lowest price for a one-way Manchester Airport to McGhee Tyson Airport flight. A return flight starts from £570. These prices can change based on availability.
Don't wait until the last minute. You're more likely to get cheap tickets from MAN to TYS if you book in advance. Airlines often offer some excellent early bird deals.
Getting cheap flights from Manchester Airport to McGhee Tyson Airport is easier if you're flexible with your travel plans. Use the 'Whole month' function to see the lowest prices throughout the month and score a great deal.
There's no need to check back in every day to find out if fares have dropped when you set up a Price Alert. We'll send you an update as soon as there's a better deal on cheap flights from MAN to TYS.
Choose your preferred arrival and departure times, airlines and number of stops with the filters. Or sort your results by 'Cheapest' to find the best deals on flights from Manchester Airport to McGhee Tyson Airport.

Handy information about Manchester Airport (MAN)

When it comes to Manchester Airport's on-time performance, data shows 59.39% of flights complete their journey on time.
Central Manchester to Manchester Airport is around 11 miles. Depending on traffic, it'll take about 30 minutes to get there if you're ride-sharing, catching a cab or driving.
The trip on public transport takes about 1 hour 5 minutes.
Get your break off to a stress-free start by staying near MAN. Whether you're taking an early flight from Manchester Airport to McGhee Tyson Airport or want to avoid feeling rushed, these hotels are ideal:

Arriving at McGhee Tyson Airport (TYS)

Consider booking a hotel near TYS if you're on a late Manchester Airport to McGhee Tyson Airport flight. Check in to one of these options and skip the long transfer after landing:
Go wherever you want, whenever you want with a McGhee Tyson Airport rental car. Pick up your wheels from Budget, Alamo or Avis and see more of Knoxville and beyond.
Booking your ride from McGhee Tyson Airport around three weeks ahead gives you the best chance of locking in a great deal.

Getting from McGhee Tyson Airport (TYS) to central Knoxville

The address for TYS is 2055 Alcoa Highway.
From McGhee Tyson Airport, Knoxville is approximately 14 miles away. It takes around 20 minutes to reach the centre by car.

When to fly to McGhee Tyson Airport (TYS)

The quietest month for a flight from Manchester Airport to McGhee Tyson Airport is February, while July is the busiest. Choose the ideal time to visit Knoxville based on whether you prefer a more fast-paced or easygoing experience.
When reserving your flight from Manchester Airport to McGhee Tyson Airport, think about the kind of weather you enjoy. July is the warmest month in Knoxville, with the temperature ranging from 17ºC (63ºF) to 32ºC (90ºF).
January has average temperatures of between -6ºC (21ºF) and 11ºC (52ºF). Look for cheap tickets from MAN to TYS around that time if you like travelling in cooler conditions.

Explore more of United States

Knoxville is easy to fall in love with, but there are so many other corners of United States just waiting to be discovered. Around 280 miles north of Knoxville, a trip to Columbus will keep your itinerary packed. Start with popular sights like Franklin Park Conservatory and Botanical Gardens, Ohio Statehouse and German Village.
Indianapolis is another favourite destination in United States and is around 290 miles north-west of Knoxville. No trip is complete without visiting The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo.