Cheap Flights from Knoxville (TYS) to Manchester (MAN)

Compare Knoxville to Manchester flight deals

Find the cheapest month or even day of the year to fly to Manchester

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Flight deals from Knoxville to Manchester

Looking for a cheap last-minute deal or the best return flight from Knoxville to Manchester? Find the lowest prices on one-way and return tickets right here.

Manchester.£540 per passenger.Departing Thu, 9 Apr, returning Thu, 16 Apr.Return flight with Allegiant Air and Ryanair.Outbound indirect flight with Allegiant Air, departs from Knoxville on Thu, 9 Apr, arriving in Manchester.Inbound indirect flight with Ryanair, departs from Manchester on Thu, 16 Apr, arriving in Knoxville.Price includes taxes and charges.From £540, select.

Manchester.£575 per passenger.Departing Fri, 11 Dec, returning Sat, 16 Jan.Return flight with KLM.Outbound indirect flight with KLM, departs from Knoxville on Fri, 11 Dec, arriving in Manchester.Inbound indirect flight with KLM, departs from Manchester on Sat, 16 Jan, arriving in Knoxville.Price includes taxes and charges.From £575, select.

Manchester.£578 per passenger.Departing Thu, 26 Feb, returning Thu, 5 Mar.Return flight with KLM.Outbound indirect flight with KLM, departs from Knoxville on Thu, 26 Feb, arriving in Manchester.Inbound indirect flight with KLM, departs from Manchester on Thu, 5 Mar, arriving in Knoxville.Price includes taxes and charges.From £578, select.

Manchester.£595 per passenger.Departing Fri, 8 May, returning Sat, 16 May.Return flight with Allegiant Air and Ryanair.Outbound indirect flight with Allegiant Air, departs from Knoxville on Fri, 8 May, arriving in Manchester.Inbound indirect flight with Ryanair, departs from Manchester on Sat, 16 May, arriving in Knoxville.Price includes taxes and charges.From £595, select.

Manchester.£758 per passenger.Departing Fri, 6 Mar, returning Mon, 16 Mar.Return flight with Allegiant Air and Ryanair.Outbound indirect flight with Allegiant Air, departs from Knoxville on Fri, 6 Mar, arriving in Manchester.Inbound indirect flight with Ryanair, departs from Manchester on Mon, 16 Mar, arriving in Knoxville.Price includes taxes and charges.From £758, select.

Find the cheapest month to fly from Knoxville to Manchester

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Knoxville to Manchester flights are currently cheapest in April.

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Knoxville to Manchester: Alternative routes

Compare routes from Knoxville to Manchester below. You may find an airport to fly into that's cheaper, faster, or easier than Manchester.

Knoxville to Manchester: Flight information

The things to know before you go.

Cheapest flight found	£540
Cheapest month to fly	April

Finding cheap flights from Knoxville to Manchester: Frequently asked questions

How much are return flights from Knoxville to Manchester?

The best price we found for a return flight from Knoxville to Manchester is £540. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Knoxville to Manchester?

Currently, there are no airlines that fly direct from Knoxville to Manchester. But we found flights with one or more stops from £540.

How many flights are there a week from Knoxville to Manchester?

As of February 2026, there are no flights flying from Knoxville to Manchester.

When is the cheapest time to fly from Knoxville to Manchester?

The cheapest month to fly from Knoxville to Manchester is usually April.

Which upcoming date is cheapest to fly from Knoxville Airport to Manchester Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Knoxville Airport to Manchester Airport on Thursday, 9 April 2026.

Can I get a direct flight from Knoxville Airport to Manchester Airport?

No airlines currently offer direct flights between Knoxville Airport and Manchester Airport. Most routes have one or more stops.

How can I find the best flight deal to Manchester?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Manchester but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Manchester?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Manchester is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly from Knoxville Airport to Manchester with?

Currently, Allegiant Air offers the cheapest flight tickets to Manchester.

Flying from McGhee Tyson Airport (TYS) to Manchester Airport (MAN): what you need to know

Manchester is four hours ahead of Knoxville and is in the UTC+0 timezone.
Your TYS to MAN flight won't wait if you're late, so don't forget to check in on time. Arrive up to one hour in advance for domestic flights and two hours ahead when you're travelling internationally.
You can expect bigger queues during popular months such as July. Arriving up to four hours in advance for international flights and two hours for domestic departures will help ensure a smooth travel experience.

How to find the cheapest flights from McGhee Tyson Airport (TYS) to Manchester Airport (MAN)

£180 is currently the lowest price for a one-way McGhee Tyson Airport to Manchester Airport flight. A return flight starts from £540. These prices can change depending on availability.
It's often best to book ahead of time if you want to get cheap tickets from TYS to MAN. That's because airlines change prices based on demand, which tends to rise closer to departure.
If you're flexible with your trip dates, use the 'Whole month' search tool. It'll show you the cheapest price across the month when searching for a flight from McGhee Tyson Airport to Manchester Airport.
Picking up cheap flights from TYS to MAN is easy with Price Alerts. Simply create one of these automatic alerts and we'll notify you when a new discounted fare appears.
Tailor your flights with filters. Select your ideal arrival and departure times, total journey duration and airlines. You can also sort the results by 'Best,' 'Fastest' or 'Cheapest' flights from McGhee Tyson Airport to Manchester Airport.

Handy information about McGhee Tyson Airport (TYS)

You'll find TYS at 2055 Alcoa Highway.
78.98% of flights that depart McGhee Tyson Airport make it to their destination on time.
McGhee Tyson Airport is around 14 miles from central Knoxville. If you're ride-sharing, catching a cab or driving from the centre, it'll take you 20 minutes or so to get there, depending on the traffic.
Get your journey off to a relaxed start by staying near TYS. Whether you've booked an early flight from McGhee Tyson Airport to Manchester Airport or want to avoid feeling rushed, these stays are the answer:

Arriving at Manchester Airport (MAN)

Reserve a hotel close to MAN if you have a late McGhee Tyson Airport to Manchester Airport flight. Choose one of these options and skip the long transfer after landing:
Fast-track your adventure by picking up a Manchester Airport rental car. Grab a set of wheels from Green Motion, Drivalia or Surprice and experience the lesser-explored corners of Manchester and beyond.
To get the best deal, book your ride from Manchester Airport around four weeks before you set off.

Getting from Manchester Airport (MAN) to central Manchester

Manchester Airport is roughly 11 miles from central Manchester. Driving there takes about 30 minutes.
If you're travelling on public transport, expect a journey of roughly 1 hour 5 minutes.

When to fly to Manchester Airport (MAN)

August is the most popular month for flights from McGhee Tyson Airport to Manchester Airport. For a quieter experience, visit Manchester in January.
The warmest month in Manchester is July, with temperatures ranging between 9ºC (48ºF) and 23ºC (73ºF). Book your flights from McGhee Tyson Airport to Manchester Airport in this month if this is the type of weather you enjoy.
January sees average temperatures of between -1ºC (30ºF) and 7ºC (45ºF). Look for cheap tickets from TYS to MAN around that time if you'd rather travel in cooler conditions.

Explore more of United Kingdom

Manchester has its own special appeal, but there are so many other parts of United Kingdom you should also see. About 160 miles south-east of Manchester, a visit to London will keep you busy. Start with leading sights like Big Ben, The British Museum and Buckingham Palace.
If you're looking to explore another corner of United Kingdom, consider Birmingham, about 70 miles south of Manchester. Cadbury World, The Library of Birmingham and National Sea Life Centre are key highlights.