£597 Cheap Flights from Manchester (MANC) to St Louis (STL)

Q: How much are return flights from Manchester to St Louis?

The best price we found for a return flight from Manchester to St Louis is £597. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Q: Which airlines fly direct from Manchester to St Louis?

Currently, there are no airlines that fly direct from Manchester to St Louis. But we found flights with one stop from £597.

Q: How many flights are there a week from Manchester to St Louis?

As of June 2025, there are no flights flying from Manchester to St Louis.

Q: When is the cheapest time to fly from Manchester to St Louis?

The cheapest month to fly from Manchester to St Louis is usually June 2025.

Q: Which upcoming date is cheapest to fly from Manchester to St Louis Airport on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Manchester to St Louis Airport on Thursday, 19 June 2025 .

Q: Can I get a direct flight from Manchester to St Louis Airport?

No airlines currently offer direct flights between Manchester and St Louis Airport. Most routes have one or more stops.

Q: How can I find the best flight deal to St Louis?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to St Louis but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

Q: When is the best time to book flights to St Louis?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to St Louis is around 40 days in advance, so don’t leave your flight to the last minute.

Q: Which is the cheapest airline to fly from Manchester to St Louis with?

The cheapest airline that flies to St Louis is Ryanair .

Compare Manchester to St Louis flight deals

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Flight deals from Manchester to St Louis

Looking for a cheap last-minute deal or the best return flight from Manchester to St Louis? Find the lowest prices on one-way and return tickets right here.

St Louis.£597 per passenger.Departing Thu, 19 Jun, returning Thu, 10 Jul.Return flight with Ryanair and Spirit Airlines.Outbound indirect flight with Ryanair, departs from Manchester on Thu, 19 Jun, arriving in St Louis.Inbound indirect flight with Spirit Airlines, departs from St Louis on Thu, 10 Jul, arriving in Manchester.Price includes taxes and charges.From £597, select.

St Louis.£638 per passenger.Departing Wed, 10 Sep, returning Thu, 18 Sep.Return flight with Virgin Atlantic and Spirit Airlines.Outbound indirect flight with Virgin Atlantic, departs from Manchester on Wed, 10 Sep, arriving in St Louis.Inbound indirect flight with Spirit Airlines, departs from St Louis on Thu, 18 Sep, arriving in Manchester.Price includes taxes and charges.From £638, select.

St Louis.£642 per passenger.Departing Wed, 9 Jul, returning Fri, 18 Jul.Return flight with Virgin Atlantic and Spirit Airlines.Outbound indirect flight with Virgin Atlantic, departs from Manchester on Wed, 9 Jul, arriving in St Louis.Inbound indirect flight with Spirit Airlines, departs from St Louis on Fri, 18 Jul, arriving in Manchester.Price includes taxes and charges.From £642, select.

St Louis.£662 per passenger.Departing Wed, 24 Sep, returning Thu, 2 Oct.Return flight with Virgin Atlantic and Spirit Airlines.Outbound indirect flight with Virgin Atlantic, departs from Manchester on Wed, 24 Sep, arriving in St Louis.Inbound indirect flight with Spirit Airlines, departs from St Louis on Thu, 2 Oct, arriving in Manchester.Price includes taxes and charges.From £662, select.

St Louis.£669 per passenger.Departing Fri, 11 Jul, returning Sat, 2 Aug.Return flight with Virgin Atlantic and Spirit Airlines.Outbound indirect flight with Virgin Atlantic, departs from Manchester on Fri, 11 Jul, arriving in St Louis.Inbound indirect flight with Spirit Airlines, departs from St Louis on Sat, 2 Aug, arriving in Manchester.Price includes taxes and charges.From £669, select.

St Louis.£675 per passenger.Departing Sat, 4 Oct, returning Thu, 9 Oct.Return flight with British Airways and Frontier Airlines.Outbound indirect flight with British Airways, departs from Manchester on Sat, 4 Oct, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departs from St Louis on Thu, 9 Oct, arriving in Manchester.Price includes taxes and charges.From £675, select.

St Louis.£730 per passenger.Departing Mon, 20 Oct, returning Sun, 2 Nov.Return flight with Vueling Airlines and Lufthansa.Outbound indirect flight with Vueling Airlines, departs from Manchester on Mon, 20 Oct, arriving in St Louis.Inbound indirect flight with Lufthansa, departs from St Louis on Sun, 2 Nov, arriving in Manchester.Price includes taxes and charges.From £730, select.

St Louis.£752 per passenger.Departing Tue, 10 Jun, returning Fri, 5 Sep.Return flight with Scandinavian Airlines.Outbound indirect flight with Scandinavian Airlines, departs from Manchester on Tue, 10 Jun, arriving in St Louis.Inbound indirect flight with Scandinavian Airlines, departs from St Louis on Fri, 5 Sep, arriving in Manchester.Price includes taxes and charges.From £752, select.

The cheapest month to fly from Manchester to St Louis Airport

We’re always keeping an eye on fares, to help you find the lowest one in seconds. Check out the Manchester to St Louis Airport flight prices forecast over the next 12 months.

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Cheapest month:September

Most expensive month:April

Manchester to St Louis: Alternative routes

Compare routes from Manchester to St Louis below. You may find an airport to fly into that's cheaper, faster, or easier than St Louis.

Manchester to St Louis: Flight information

The things to know before you go.

Cheapest flight found	£597
Cheapest month to fly	June

Finding cheap flights from Manchester to St Louis: Frequently asked questions

How much are return flights from Manchester to St Louis?

Which airlines fly direct from Manchester to St Louis?

How many flights are there a week from Manchester to St Louis?

When is the cheapest time to fly from Manchester to St Louis?

Which upcoming date is cheapest to fly from Manchester to St Louis Airport on?

Can I get a direct flight from Manchester to St Louis Airport?

How can I find the best flight deal to St Louis?

When is the best time to book flights to St Louis?

Which is the cheapest airline to fly from Manchester to St Louis with?

How to find cheap flights to St Louis from Manchester

Looking for cheap tickets from Manchester to St Louis? Here are a few tips on how to secure the best flight price and make your journey as smooth as possible.

Simply hit 'search'. From British Airways to international carriers like Emirates, we compare all major airlines along with the most popular online travel agents to find the cheapest plane tickets from Manchester to St Louis. And with us there are no hidden fees - what you see is what you pay.
Compare flight deals to St Louis from Manchester from over 1,000 providers. Then choose the cheapest or fastest plane tickets.
Flex your dates to find the best Manchester-St Louis ticket prices. If you are flexible when it comes to your travel dates, use Skyscanner's 'Whole month' tool to find the cheapest month, and even day to fly to St Louis from Manchester.
Set up a Price Alert. You can easily track the fare of your cheap Manchester-St Louis flights by creating an alert. Whenever prices go down or up, you'll get an email or push notification to help make sure you get the best possible flight deal.
Fly without stops. Only interested in direct flights between Manchester and St Louis? Make sure to tick 'Direct flights only' when performing a search. If there are direct flights available on the route, these will appear in the results.
Find the cheapest Business class flights from Manchester and St Louis. We scour the internet for the best Business, Premium Economy and First Class flight fares to St Louis, too. Check the difference in price as you search – you might just chance upon a last-minute low fare. Note that not all cabin classes are available for every destination or airline.
Include nearby airports in your search. Widen your search for Manchester to St Louis flight deals by selecting the "add nearby airports" option. This will allow you to see flight prices for all the nearest airports at your departure point and your destination and could help you save next time you travel.

Combine your flight to St Louis from Manchester with hotels and car hire

Once you've secured your cheap flight ticket from Manchester to St Louis, discover the best prices and exclusive rates for hotels in St Louis or nearby. You can also compare hundreds of car hire companies in one go so that you get the best car hire price for your trip.