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Cheap Flights from Chicago to Irvine

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      Travellers and cabin class, 1 Adult, Economy

      Compare Chicago to Irvine flight deals

      Find the cheapest month or even day of the year to fly to Irvine

      Book the best Irvine fare with no extra fees

      Flight deals from Chicago to Irvine

      Looking for a cheap last-minute deal or the best return flight from Chicago to Irvine? Find the lowest prices on one-way and return tickets right here.
      Santa Ana.£46 per passenger.Departing Wed, 30 Sep.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Chicago O'Hare International on Wed, 30 Sep, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £46, select.
      Santa Ana.£56 per passenger.Departing Thu, 13 Aug.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Chicago O'Hare International on Thu, 13 Aug, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £56, select.
      Santa Ana.£86 per passenger.Departing Mon, 2 Nov.One-way flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Chicago Midway on Mon, 2 Nov, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £86, select.
      Santa Ana.£94 per passenger.Departing Thu, 1 Oct.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Chicago Midway on Thu, 1 Oct, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £94, select.
      Santa Ana.£98 per passenger.Departing Wed, 29 Jul.One-way flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Chicago O'Hare International on Wed, 29 Jul, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £98, select.
      Santa Ana.£115 per passenger.Departing Tue, 15 Dec.One-way flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Chicago Midway on Tue, 15 Dec, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £115, select.
      Santa Ana.£116 per passenger.Departing Sat, 16 Jan.One-way flight with Alaska Airlines.Outbound indirect flight with Alaska Airlines, departs from Chicago O'Hare International on Sat, 16 Jan, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £116, select.
      Santa Ana.£116 per passenger.Departing Sat, 29 May.One-way flight with Alaska Airlines.Outbound indirect flight with Alaska Airlines, departs from Chicago O'Hare International on Sat, 29 May, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £116, select.
      Santa Ana.£116 per passenger.Departing Mon, 1 Feb.One-way flight with Alaska Airlines.Outbound indirect flight with Alaska Airlines, departs from Chicago O'Hare International on Mon, 1 Feb, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £116, select.
      Santa Ana.£121 per passenger.Departing Wed, 28 Oct.One-way flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Wed, 28 Oct, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £121, select.
      Santa Ana.£140 per passenger.Departing Fri, 16 Apr.One-way flight with Alaska Airlines.Outbound indirect flight with Alaska Airlines, departs from Chicago O'Hare International on Fri, 16 Apr, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £140, select.
      Santa Ana.£217 per passenger.Departing Fri, 19 Mar.One-way flight with Alaska Airlines.Outbound indirect flight with Alaska Airlines, departs from Chicago O'Hare International on Fri, 19 Mar, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £217, select.
      Santa Ana.£226 per passenger.Departing Tue, 15 Sep.One-way flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Tue, 15 Sep, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £226, select.
      Santa Ana.£226 per passenger.Departing Tue, 15 Dec.One-way flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Tue, 15 Dec, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £226, select.
      Santa Ana.£226 per passenger.Departing Wed, 12 Aug.One-way flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Wed, 12 Aug, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £226, select.
      Santa Ana.£226 per passenger.Departing Thu, 12 Nov.One-way flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Thu, 12 Nov, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £226, select.
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      Chicago to Irvine: Flight information

      The things to know before you go.
      Fly intoSanta Ana John Wayne Airport
      Distance to Irvine4.2 miles
      Cheapest flight£46
      Cheapest month to flySeptember
      Most popular airlineAmerican Airlines
      Average flight time4 hrs, 29 mins

      Find the cheapest month to fly from Chicago to Irvine

      We always keep an eye on fares, so you can find the best flight deal in seconds. It looks like Chicago to Irvine flights are currently cheapest in October. We’ve based this on flights into Santa Ana John Wayne Airport.
      Jul
      from £98
      Aug
      from £56
      Sep
      from £46
      Oct
      from £94
      Nov
      from £86
      Dec
      from £115
      Jan
      from £116
      Feb
      from £116
      Mar
      from £217
      Apr
      from £140
      May
      from £116
      Jun
      Find prices

      Finding cheap flights from Chicago to Irvine: Frequently asked questions

      There are 3 airports near Irvine: Santa Ana John Wayne Airport, Long Beach Municipal Airport and Ontario International Airport.
      The best price we found for a return flight from Chicago to Irvine is £125. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      American Airlines, Alaska Airlines, United all offer direct flights to Santa Ana John Wayne Airport.
      We've checked every Chicago to Irvine fare we could find, and the cheapest upcoming date to fly seems to be on Thursday, 1 October 2026. Overall, the cheapest month to fly from Chicago to Irvine is usually October.
      If you're flying from Chicago, the cheapest airport near Irvine is Santa Ana John Wayne – which is 4.2 miles away from the centre of Irvine. We've found flights into this airport from £125.
      After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Chicago to Irvine on Thursday, 1 October 2026.
      No airlines currently offer direct flights between Chicago and Irvine. Most routes have one or more stops.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Irvine but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Irvine is around 40 days in advance, so don’t leave your flight to the last minute.

      Santa Ana John Wayne Airport is 4.2 miles from Irvine, Long Beach Municipal Airport is 22.5 miles from Irvine, and Ontario International Airport is 27.9 miles from Irvine.
      Santa Ana John Wayne Airport is closest to Irvine, at around 4.2 miles away.
      The cheapest airline that flies to Irvine is Frontier Airlines. And the cheapest airline that flies to Long Beach Municipal Airport is United.

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