Cheap Flights from Santiago (SCU) to Santo Domingo (SDQA)

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      Travellers and cabin class, 1 Adult, Economy
      Sky High Aviation Services
      Air Century
      Hahn Air Technologies
      Euroairlines, S.L.

      Compare Santiago to Santo Domingo flight deals

      Find the cheapest month or even day of the year to fly to Santo Domingo

      Book the best Santo Domingo fare with no extra fees

      Flight deals from Santiago to Santo Domingo

      Looking for a cheap last-minute deal or the best return flight from Santiago Airport to Santo Domingo? If you want to travel next month, return fares start from £309. Find the lowest prices on one-way and return tickets right here.
      How did we find these deals? The deals you see here are the lowest prices for flight tickets from Santiago to Santo Domingo found in the last 4 days, and are subject to change and availability.

      Find the cheapest month to fly from Santiago to Santo Domingo

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santiago to Santo Domingo flights are currently cheapest in December.

      Direct flights from Santiago to Santo Domingo

      Air Century
      Euroairlines, S.L.
      Hahn Air Technologies
      Sky High Aviation Services

      Alternative Santiago to Santo Domingo routes

      Looking for the cheapest, fastest or easiest route from Santiago to Santo Domingo? You could fly into the following airports instead.

      Santiago to Santo Domingo: Flight information

      The things to know before you go.
      Cheapest flight found£293
      Cheapest month to flyDecember
      Average flight time1 hr, 10 mins
      Most popular airlineSky High Aviation Services
      Average flights per week8

      Finding cheap flights from Santiago to Santo Domingo: Frequently asked questions

      There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
      The best price we found for a return flight from Santiago to Santo Domingo is £309. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      1 hour and 7 minutes is the average flight time from Santiago to Santo Domingo.
      Air Century, Hahn Air Technologies and Euroairlines, S.L. fly direct from Santiago to Santo Domingo.
      As of September 2026, there are 7 flights per week flying from Santiago to Santo Domingo.
      The cheapest month to fly from Santiago to Santo Domingo is usually October.
      If you're flying from Santiago Airport, the cheapest airport near Santo Domingo is La Isabela International – which is 9.3 miles away from the centre of Santo Domingo. We've found flights into this airport from £309.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Santiago Airport to Santo Domingo on Monday, 12 October 2026.
      Yes – the average flight time is 1 hour and 9 minutes.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.

      In September, the average temperature is usually around 28°C. August is typically the warmest month in Santo Domingo, when it usually averages around 32°C. You can expect the least rain in January. The coldest month is January, with temperatures averaging 20°C. The rainiest month is August.
      Currently, Euroairlines, S.L. offers the cheapest flight tickets to Santo Domingo.

      Travelling from Santiago de Cuba Antonio Maceo Intl Airport (SCU) to Santo Domingo: what you need to know

      • The average duration of a direct flight from Santiago de Cuba Antonio Maceo Intl Airport to Santo Domingo is 2 hours.

      • Santiago de Cuba Antonio Maceo Intl Airport is located in Santiago. Following the UTC-4 timezone, Santo Domingo is one hour ahead of Santiago.

      • For a smooth journey, arrive at the airport two hours ahead of international flights and one hour before domestic departures. This will give you plenty of time to catch your SCU to Santo Domingo flight.

      • You'll likely experience longer lines in popular months such as August. Arriving up to four hours ahead of an international flight and two hours for a domestic departure is a good idea.

      • Direct Santiago de Cuba Antonio Maceo Intl Airport to Santo Domingo tickets are available for booking. Santo Domingo Las Americas International Airport (SDQ) is where you'll complete your journey.

      • Keep your eyes peeled for offers from Air Century. This airline has direct flights from Santiago de Cuba Antonio Maceo Intl Airport to Santo Domingo.

      • Finding a plane ticket from SCU to Santo Domingo with a stopover is a breeze. Whether you're eager to cut costs on your fare or add a new city to your itinerary, just deselect 'Direct flights only' to view your options. A major stop is Miami International Airport (MIA).

      • SCU is around 5 kms (3 miles) from central Santiago. If you're driving, ride-sharing or catching a taxi from the centre, it'll take 25 minutes or so to get there, depending on traffic conditions. If you're planning to take public transport, expect the trip time to be around 45 minutes.

      • Catching an early flight from Santiago de Cuba Antonio Maceo Intl Airport to Santo Domingo? Avoid the stress of rushing to the terminal (and sneak in some extra precious sleep) by choosing one of these stays near SCU:

      • Of all flights leaving Santiago de Cuba Antonio Maceo Intl Airport, 76% arrive as scheduled at their destination.

      How to find the cheapest flights from Santiago de Cuba Antonio Maceo Intl Airport (SCU) to Santo Domingo

      • £293 is the lowest price we've found for a one-way Santiago de Cuba Antonio Maceo Intl Airport to Santo Domingo flight. A round-trip ticket right now is £309. Depending on the availability when you book, these fares may change.

      • Don't wait until the last minute. You're more likely to find cheap flights from SCU to Santo Domingo if you book early. Airlines often offer some fantastic early bird rates.

      • If you have flexibility with your travel plans, try using the 'Whole month' tool. It'll find the lowest price across every month when searching for a Santiago de Cuba Antonio Maceo Intl Airport to Santo Domingo ticket.

      • Finding a cheap flight from SCU to Santo Domingo couldn't be easier with Price Alerts. All you need to do is set up one of these automatic notifications and we'll notify you when a lower fare pops up.

      • Tailor your flights with filters. Select your ideal arrival and departure times, total journey duration and airlines. You can also sort the results by 'Cheapest,' 'Fastest' or 'Best' flights from Santiago de Cuba Antonio Maceo Intl Airport to Santo Domingo.

      Airports in Santo Domingo

      Santo Domingo Las Americas International Airport (SDQ)

      • The distance from Santo Domingo Las Americas International Airport (SDQ) to central Santo Domingo is roughly 29 kms (18 miles). It'll take you about 35 minutes to get to the centre driving.

      • When travelling by public transport, expect a journey time of about 1 hour 15 minutes.

      • If you're arriving on a late flight from Santiago de Cuba Antonio Maceo Intl Airport to Santo Domingo, nothing beats the convenience of staying close to the terminal. Pick up your bags from the carousel and then be showered and resting soon after at one of these accommodation options near SDQ:

      • To secure the lowest price, book your ride from Santo Domingo Las Americas International Airport about one week ahead of your flight from SCU to Santo Domingo.

      La Isabela Dr Joaquin Balaguer Intl Airport (JBQ)

      • Central Santo Domingo is about 23 kms (14 miles) from La Isabela Dr Joaquin Balaguer Intl Airport (JBQ). After your flight from Santiago de Cuba Antonio Maceo Intl Airport to Santo Domingo has hit the runway and you've made your way through the terminal, expect a drive of around 30 minutes.

      • If you're travelling on public transport, it'll take about 50 minutes.

      • Following your SCU to Santo Domingo flight, kick back at a hotel close to JBQ. These are some comfortable accommodation options that'll help you get into relaxation mode:

      • Typically, the earlier you book, the better the prices and selection of vehicles. Secure your ride from JBQ once you know your travel dates.

      Best time to go to Santo Domingo

      • It's time to choose your trip dates for your flight from Santiago de Cuba Antonio Maceo Intl Airport to Santo Domingo. August is the busiest month to visit Santo Domingo. If you prefer a quieter vibe, go in December.

      • Book a Santiago de Cuba Antonio Maceo Intl Airport to Santo Domingo plane ticket with a departure in September if you want to experience the city during its warmest month. You can expect temperatures to range from 23ºC to 33ºC.

      • February has average temperatures of between 19ºC and 29ºC. Search for a cheap ticket from SCU to Santo Domingo around that time if you like travelling in cooler conditions.

      More about Santo Domingo

      • After booking your flight from Santiago de Cuba Antonio Maceo Intl Airport to Santo Domingo, find a hotel that offers both comfort and a great location. Make one of these accommodation options your base for exploring Santo Domingo:

      • Alcazar de Colon and Catedral Primada de las Americas are just two of the top attractions to add to your Santo Domingo must-do list. Keep the adventure rolling by checking out The Cathedral of the Americas.

      Explore more of the Dominican Republic

      • You've seen Santo Domingo, now it's time to discover other parts of the Dominican Republic. Travel about 105 kms (65 miles) east to La Romana to check off its top sights. From Altos de Chavon to Minitas Beach and Dye Fore Golf Course of Casa de Campo, there's plenty to keep you busy.

      • Around 161 kms (100 miles) northwest of Santo Domingo, Puerto Plata is another essential stop in the Dominican Republic. Experience major highlights starting with Long Beach, Golden Beach (Playa Dorada) and Puerto Plata Cable Car.

      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.