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Cheap Flights from Milan Malpensa (MXP) to Sao Tome Is (TMS)

Compare Milan Malpensa to Sao Tome Is flight deals

Find the cheapest month or even day of the year to fly to Sao Tome Is

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Flight deals from Milan Malpensa to Sao Tome Is

Looking for a cheap last-minute deal or the best return flight from Milan Malpensa to Sao Tome Is? Find the lowest prices on one-way and return tickets right here.
Sao Tome Is.£557 per passenger.Departing Mon, 9 Mar, returning Wed, 18 Mar.Return flight with easyJet and TAAG Angola Airlines.Outbound indirect flight with easyJet, departs from Milan Malpensa on Mon, 9 Mar, arriving in Sao Tome Is.Inbound indirect flight with TAAG Angola Airlines, departs from Sao Tome Is on Wed, 18 Mar, arriving in Milan Malpensa.Price includes taxes and charges.From £557, select.
Sao Tome Is.£600 per passenger.Departing Mon, 21 Sep, returning Wed, 30 Sep.Return flight with easyJet and TAAG Angola Airlines.Outbound indirect flight with easyJet, departs from Milan Malpensa on Mon, 21 Sep, arriving in Sao Tome Is.Inbound indirect flight with TAAG Angola Airlines, departs from Sao Tome Is on Wed, 30 Sep, arriving in Milan Malpensa.Price includes taxes and charges.From £600, select.
Sao Tome Is.£623 per passenger.Departing Sat, 3 Oct, returning Fri, 16 Oct.Return flight with Ryanair and TAAG Angola Airlines.Outbound indirect flight with Ryanair, departs from Milan Malpensa on Sat, 3 Oct, arriving in Sao Tome Is.Inbound indirect flight with TAAG Angola Airlines, departs from Sao Tome Is on Fri, 16 Oct, arriving in Milan Malpensa.Price includes taxes and charges.From £623, select.
Sao Tome Is.£697 per passenger.Departing Thu, 2 Apr, returning Wed, 8 Apr.Return flight with Wizz Air Malta and TAAG Angola Airlines.Outbound indirect flight with Wizz Air Malta, departs from Milan Malpensa on Thu, 2 Apr, arriving in Sao Tome Is.Inbound indirect flight with TAAG Angola Airlines, departs from Sao Tome Is on Wed, 8 Apr, arriving in Milan Malpensa.Price includes taxes and charges.From £697, select.
Sao Tome Is.£702 per passenger.Departing Tue, 8 Dec, returning Sat, 19 Dec.Return flight with easyJet and TAP Air Portugal.Outbound indirect flight with easyJet, departs from Milan Malpensa on Tue, 8 Dec, arriving in Sao Tome Is.Inbound indirect flight with TAP Air Portugal, departs from Sao Tome Is on Sat, 19 Dec, arriving in Milan Malpensa.Price includes taxes and charges.From £702, select.
Sao Tome Is.£733 per passenger.Departing Wed, 1 Jul, returning Wed, 22 Jul.Return flight with easyJet and TAAG Angola Airlines.Outbound indirect flight with easyJet, departs from Milan Malpensa on Wed, 1 Jul, arriving in Sao Tome Is.Inbound indirect flight with TAAG Angola Airlines, departs from Sao Tome Is on Wed, 22 Jul, arriving in Milan Malpensa.Price includes taxes and charges.From £733, select.
Sao Tome Is.£736 per passenger.Departing Mon, 27 Apr, returning Sun, 3 May.Return flight with Vueling Airlines and TAP Air Portugal.Outbound indirect flight with Vueling Airlines, departs from Milan Malpensa on Mon, 27 Apr, arriving in Sao Tome Is.Inbound indirect flight with TAP Air Portugal, departs from Sao Tome Is on Sun, 3 May, arriving in Milan Malpensa.Price includes taxes and charges.From £736, select.
Sao Tome Is.£741 per passenger.Departing Sat, 14 Nov, returning Sat, 21 Nov.Return flight with TAP Air Portugal.Outbound indirect flight with TAP Air Portugal, departs from Milan Malpensa on Sat, 14 Nov, arriving in Sao Tome Is.Inbound indirect flight with TAP Air Portugal, departs from Sao Tome Is on Sat, 21 Nov, arriving in Milan Malpensa.Price includes taxes and charges.From £741, select.

Find the cheapest month to fly from Milan Malpensa to Sao Tome Is

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Milan Malpensa to Sao Tome Is flights are currently cheapest in March.
Feb
from £902
Mar
from £557
Apr
from £697
May
Find prices
Jun
from £749
Jul
from £733
Aug
from £806
Sep
from £600
Oct
from £623
Nov
from £741
Dec
from £702
Jan
from £909

Milan Malpensa to Sao Tome Is: Alternative routes

Compare routes from Milan Malpensa to Sao Tome Is below. You may find an airport to fly into that's cheaper, faster, or easier than Sao Tome Is.

Sao Tome Is

3 miles from central Sao Tome Is
ClosestCheapest
from £557
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Milan to Sao Tome Is: Flight information

The things to know before you go.
Cheapest flight found£557
Cheapest month to flyMarch

Finding cheap flights from Milan Malpensa to Sao Tome Is: Frequently asked questions

The best price we found for a return flight from Milan Malpensa to Sao Tome Is is £557. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Milan Malpensa to Sao Tome Is. But we found flights with one or more stops from £557.
As of February 2026, there are no flights flying from Milan Malpensa to Sao Tome Is.
The cheapest month to fly from Milan Malpensa to Sao Tome Is is usually March.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Milan Malpensa Airport to Sao Tome Is Airport on Monday, 9 March 2026.
No airlines currently offer direct flights between Milan Malpensa Airport and Sao Tome Is Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Sao Tome Is but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Sao Tome Is is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, easyJet offers the cheapest flight tickets to Sao Tome Is.

How to find cheap flights to Sao Tome Is (TMS) from Milan (MXP) in 2026

Looking for cheap tickets from Milan Malpensa to Sao Tome Is? Return tickets start from £557 and one-way flights to Sao Tome Is from Milan Malpensa start from £322


Here are a few tips on how to secure the best flight price and make your journey as smooth as possible.

  • Simply hit 'search'. From British Airways to international carriers like Emirates, we compare all major airlines along with the most popular online travel agents to find the cheapest plane tickets from Milan Malpensa to Sao Tome. And with us there are no hidden fees - what you see is what you pay.
  • Compare flight deals to Sao Tome Is from Milan from over 1,000 providers. Then choose the cheapest or fastest plane tickets. Flight tickets to Sao Tome Is start from £322 one-way.
  • Flex your dates to find the best MXP-TMS ticket prices. If you are flexible when it comes to your travel dates, use Skyscanner's 'Whole month' tool to find the cheapest month, and even day to fly to Sao Tome Is from Milan Malpensa.
  • Set up a Price Alert. You can easily track the fare of your cheap Milan Malpensa-Sao Tome flights by creating an alert. Whenever prices go down or up, you'll get an email or push notification to help make sure you get the best possible flight deal.
  • Flexible on when you travel? The cheapest month to fly from Milan Malpensa to Sao Tome Is is March.
  • Fly without stops. Only interested in direct flights between Milan Malpensa and Sao Tome Is? Make sure to tick 'Direct flights only' when performing a search. If there are direct flights available on the route, these will appear in the results.
  • Find the cheapest Business class flights from Milan Malpensa and Sao Tome Is. We scour the internet for the best Business, Premium Economy and First Class flight fares to Sao Tome Is, too. Check the difference in price as you search – you might just chance upon a last-minute low fare. Note that not all cabin classes are available for every destination or airline.
  • Include nearby airports in your search. Widen your search for Milan Malpensa to Sao Tome Is flight deals by selecting the "add nearby airports" option. This will allow you to see flight prices for all the nearest airports at your departure point and your destination and could help you save next time you travel.
  • Search for cheap flights regardless of where you are. To get the best flight booking experience when out and about, download the app and search for plane tickets between Milan Malpensa and Sao Tome Is whenever you want.

Combine your flight to Sao Tome Is from Milan Malpensa with hotels and car hire

Once you've secured your cheap flight ticket from Milan Malpensa to Sao Tome Is, discover the best prices and exclusive rates for hotels in Sao Tome Is or nearby. You can also compare hundreds of car hire companies in one go so that you get the best car hire price for your trip.


Plan the rest of your trip from Milan to Sao Tome Is

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.