It is best to avoid peak hours (weekdays from 05:05 until 09:15).
Start looking for advance tickets 24 weeks before you're planning to travel - this is when Virgin Trains release their cheapest rates.
The average train journey time from Manchester to London is 2 hours and 10 minutes. All trains are direct, so there are no changes to slow things down. Stops en route include Stockport, Wilmslow, Crewe and Nuneaton.
Trains to London depart from Manchester Piccadilly train station, and are operated by Virgin Trains.
Trains from Manchester Piccadilly arrive at London Euston train station, just around the corner from Kings Cross and St Pancras International. It's a 15 minute walk if you're planning on catching the Eurostar.
Euston station is well connected to the rest of London by underground - the Circle, Hammersmith & City and Metropolitan lines all stop here. Take a short stroll over to Kings Cross underground for the Northern, Piccadilly and Victoria lines.
The first direct train departs Manchester Piccadilly at 05:05 and arrives in London at 07:26. The last leaves at 21:15 and arrives in London Euston at 23:48. If you're planning on staying over, you can use our app to find the most convenient (and best priced) hotels in London.
Trains leave every 10 to 20 minutes during the day, with more frequent departures during peak commute times.
Train timetables are subject to change: compare tickets from Manchester to London to see the latest departure times.