The service to north-west Ireland, which will depart from the airport on each consecutive Saturday, will operate until August 22nd.
East Midlands Airport’s director of marketing Caroline Plant said she was "extremely pleased and excited" that the airline would be offering flights to Donegal.
"Our Irish routes have always proved popular with passengers and we are confident that the new tailored holiday packages to Donegal, offering a variety of tradition and culture, will mean even greater choice and flexibility when booking trips to Ireland this summer," she commented.
Donegal is an attractive destination owing to the surrounding hills, glens, mountains and moors and the region’s rugged Atlantic coastline, which has the highest sea cliffs in Europe.
Elsewhere, Aurigny Air Services launched new flights to Guernsey from East Midlands Airport on May 1st.
The airline has said that the service will prove popular because more Brits are choosing to fly to domestic destinations because of the weakness of the pound against the euro. Flights to Donegal to begin from East Midlands Airport in July