The new flight will replace the existing route between Cleveland and London Gatwick after the airline’s customers expressed their desire to have a non-stop service to Europe’s most important business airport.
Commenting on the new flight, Cleveland mayor Frank Jackson said it would offer a boost to the airline’s business development efforts.
"I am optimistic that the region’s business community will support this improved service to London in a way that will warrant Continental’s consideration of extending the service year-round in the future," he said.
Continental also announced that it would be ending its seasonal route between Cleveland and Paris Charles de Gaulle Airport, a decision that has been blamed on the global financial crisis.
The new flight will be operated on Boeing 757 aircraft, which can accommodate 159 economy class passengers and 16 in the BusinessFirst cabin.
Continental is the fourth-largest airline in the US in terms of revenue passenger miles.