There is an airport here, but to get to it you have to take a six seater and land in at least three other towns on the way up from Santa Cruz, and every single one of them has a plane crash just pushed off to the side of the "runway" place where the cows graze. Otherwise it is five days in a boat from Trinidad, and then a truck ride. There is some good Brazilian steaks, and feijoada on the plaza, but otherwise good luck finding something to do. I rented a scooter with a friend and paid a fisherman to take us across the Madre de Dios river on his boat. It was an excellent trip, but beware if something goes wrong because "the clinic" is a nurse with a bad sense of humor and a stitching needle stuck in a bloody piece of gauze. Found this out the hard way, so you shouldn't not have to... If you can find some fisherman try to get them to show you a paiche (pie-chay), which is a monstrous looking fish, and the closest thing to a dinosaur I have ever seen. It eats people.